troduction: The dried root of Polygala tenuifolia Willd., known as Polygala Radix, belonging to the family Polygalaceae, has long been used as a medication to cure a variety of illnesses, including sleeplessness, forgetfulness,
sadness, cough, and palpitations. In Southeast Asia, especially China, Polygala tenuifolia Willd is a significant
industrial and export plant. The benefits of Polygala tenuifolia’s rhizomes on cognition and nootropics are wellknown. As a result, this plant has been used as traditional medicine for many of years.
Methodology: The online databases, including Scopus, web of science, Google Scholar, and PubMed, were
searched using different keywords: Polygala Radix, Polygala tenuifolia, traditional uses, neuroprotective activity,
Chinese herb. The purpose of this review was, therefore, to summarise the previously reported phytochemistry &
pharmacological actions of the chosen plant species.